In another study, female Wistar rats treated with pure tamoxifen was compared to the control group on 7,12-dimethylbenz(a)anthracene (DMBA) and to a group treated with tamoxifen loaded poly(d,l-lactic acid) (PLA) nanoparticles (NPs), the tumor size was significantly reduced in groups treated with NPs as compared to pure Tmx and untreated group [106]
The tripeptide glutathione, -L-glutamyl-L-cysteinyl-glycine, has come to the forefront as a nutritional bioactive with potential use in the management of NAFLD, as it plays a critical role in cellular antioxidant and detoxification systems
doi: 10.1615/intjmedmushrooms.v17.i7.10
However, these treatments did not directly affect MDSC survival or maturation in vitro, suggesting that their primary mode of action lies in disrupting MDSC recruitment to the TME
Kin T et al
"Pentadecapeptide BPC 157 and the central nervous system." Neural Regen Res