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VerbalisJGGoldsmithSRGreenbergAKorzeliusCSchrierRWSternsRHet al
Transient activation of autophagy during early injury phases appears cytoprotective by eliminating dysfunctional mitochondria and preventing proteotoxic stress
682 In addition, electroacupuncture promotes the synthesis and metabolism of GSH in the injured area of the cerebral cortex by activating the Xc /GSH/GPX4 axis, thereby inhibiting nerve ferroptosis in rats with TBI
In contrast, M-CuP showed negligible binding to either target, with maximal responses below 5 response units (RU) across all tested concentrations, confirming the essential role of multivalent architecture in cooperative target engagement
Further, El-Shall et al
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