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Vitamin B12deficiency can manifest itself in the following clinical pictures: Hyperchromic macrocytic megaloblastic anemia (perniciosa, Biermer anemia, Addison's anemia these are disorders of the maturation of red blood cells) Funicular spinal disease [damage to the spinal cord] A vitamin B12deficiencyconfirmed by laboratorydiagnosis can occur in: Years of malnutrition and malnutrition (e.g through strict vegetarian diet)

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Initially studied for its cytoprotective and gut-healing properties, its potential applications in research have exploded over the last decade