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The authors also reported that the use of chemotherapy has demonstrated low response rates and yielded no clear mortality benefit in the treatment of MMNST

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This includes people with pernicious anemia, a condition where the body lacks intrinsic factors, making it impossible to absorb B12 from food

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It is reasonable to take both observations seriously as hypotheses, with two cautions: Phase 2 trials are smaller, and the trial populations are not identical to GLP-1 trial populations