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For a common working concentration of 2.5 mg/mL, add 2 mL of solvent directly to the lyophilized vial and allow it to dissolve gently without vortexing, as aggressive agitation can cause peptide aggregation and loss of bioactivity

After intravenous administration, DSIP was found to have significantly lowered pain levels in six of the seven patients.20 As with the sleep trials, we should spotlight the fact that this study had a very small sample size

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These patients should have liver function testing at baseline, 1 month, and 3 months after starting either agent

10.1016/j.abb.2014.05.003 11 ChandelN

Inject the water against the inside wall of the vial never directly onto the lyophilized powder