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Overweight and obese adults who took the injected medication Mounjaro lost more weight and were more likely to meet specific weight loss targets than people on a similar competitor, Ozempic, according to a new study of people taking the drugs in the real world

Warfarin interaction is clinically relevant because GLP-1-induced changes in gastric emptying can alter absorption of narrow-therapeutic-index drugs, and QT prolongation matters because of the cardiac side-effect profile of some weight-loss adjuncts

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S., Petsko, G

Distribution favors metabolically active organs, particularly the kidneys, liver, stomach wall, and intestinal tissues