Only a small number of people need to stop treatment because of side effects
Yes, both aerobic exercise (brisk walking, cycling, swimming) and resistance training may enhance GLP-1 secretion and improve insulin sensitivity
Nearly all patients with PCOS who received a semaglutide or tirzepatide prescription also had obesity or type 2 diabetestwo conditions for which GLP-1s are FDA-approved and central to managing PCOS-related metabolic risk
While no FDA-approved tapering protocol exists, structured approaches involving alternative therapies, lifestyle intensification, and close monitoring optimize outcomes
References Bonaz, B., Bazin, T., Pellissier, S
Its also a good option for those who want to avoid prescription medications