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Theyll generally base eligibility on whether you meet the BMI threshold, whether youve tried other medications, and whether youre on an exercise and diet program
10.1016/j.tem.2016.03.017 Trends Endocrinol
Preparations Excipients in commercially available drug preparations may have clinically important effects in some individuals
With demand growing, businesses must be able to ship their GLP-1 RAs without efficacy loss
What they found: Oral AOD-9604 reduced body fat by 18 to 22 % vs placebo, comparable to injection administration No changes in total body weight (because lean mass rose slightly) Decrease in plasma triglycerides by 30 % Decrease in resting free fatty acids (paradoxically, mobilization of fat from depots into oxidation) No GI side effects Why it matters: It suggested that AOD-9604 could work orally , a rare property for a peptide
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