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Tetramethyl bisphenol A, a bisphenol analog, is used as a fire retardant, and it inhibits testosterone synthesis in late puberty by inducing ferroptosis in Leydig cells [112]
doi: 10.1186/s10020-021-00368-2 111 YangRZXuWNZhengHLZhengXFLiBJiangLSet al
These changes reduce its binding affinity to IGF-binding proteins (IGFBPs), allowing for a longer half-life (up to 2030 hours) and increased bioavailability in plasma
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EVs notably reduced the pathological traits and neuroinflammation in SOD1G93A astrocytes
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