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The most common side effect is diarrhea, although gastrointestinal symptoms are usually mild
The full glycemic effect typically develops over several weeks as the medication reaches steady-state concentrations in the bloodstream
Exendin-4 antagonizes A1-42-induced suppression of long-term potentiation by regulating intracellular calcium homeostasis in rat hippocampal neurons
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However, we eat for more reasons than physical hunger, and some people might continue to eat enough food that prevents them from achieving a calorie deficit due to psychological, environmental, or habitual reasons
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