It contains naltrexone HCI, which is more commonly used to treat substance abuse conditions, and bupropion HCI (brand name Wellbutrin), which is a very popular antidepressant
Zepbound FDAapproved since November 2023 for chronic weight management in adults with obesity or overweight and a weightrelated condition
Int J Child Neuropsychiatry 2005
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The first and original use is for type 2 diabetes management , where GLP-1 agonists help lower hemoglobin A1c levels by 1.02.0% on average, with the additional benefit of promoting modest weight loss rather than weight gain seen with some other diabetes medications
Some providers prescribe it off-label for weight loss, though the oral bioavailability is lower and the weight loss results are typically more modest than the injectable form