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10.1016/j.semcdb.2019.06.003 224 MardenJ

If left untreated, vitamin B12 deficiency can lead to neurological problems or anemia

Taurine protects from pentylenetetrazole-induced behavioral and neurochemical changes in zebrafish

Indications and Usage for Cyanocobalamin Cyanocobalamin is indicated for vitamin B 12deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue

Histidine-Containing Supplements and Amino Acid Competition GHK-Cu's histidine residue participates directly in copper coordination through its imidazole nitrogen

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