Clinicians should also consider alternative medical explanations for new-onset fatigue, including thyroid dysfunction, anemia, sleep apnea (which may improve or persist despite weight loss), chronic kidney disease, or cardiovascular conditions
These include mono agonists, glucagonlike peptide-1 receptor agonists (GLP-1 agonists), and dual agonists that combine a glucose-dependent insulinotropic polypeptide (GIP) with a GLP-1 agonist (GIP/GLP-1), which have demonstrated a 15% and greater weight loss in people with obesity and/or type 2 diabetes, says Richard E
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Research specifically examining menopausal status found no significant difference in weight loss between premenopausal, perimenopausal, and postmenopausal women using tirzepatide
When she heard about compounded GLP-1 therapy, she decided to explore these options
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