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We prefer subcutaneous, because it is painless, effective, very easy to do by yourself, and carries no risk of nerve injury

It is also unusually stable in gastric acid, which is why oral dosing is even theoretically plausible

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A proper trial is at least 812 weeks , but most people who see benefits continue beyond that because the effects are tied to ongoing use

The temptation to escalate the dose because nothing is happening yet is exactly the mistake the timeline section is designed to head off the mechanism is cumulative, not dose-chased