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Overall, the genes most highly modulated by SR4 were primarily associated with fatty acid synthesis, lipid accumulation and liver steatosis, inflammatory responses and fibrotic processes, which suggested that SR4 may exert protective effects through the coordinated regulation of hepatic metabolic and stress-response pathways

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Simpson SH, Majumdar SR, Tsuyuki RT, et al.: Dose-response relation between sulfonylurea drugs and mortality in type 2 diabetes mellitus: a population-based cohort study

Changes in brain membrane phospholipid and high-energy phosphate metabolism precede dementia Neurobiol Aging 1995

It has not been proven to be an effective treatment for cancer

CrossRef Therapeutic effect of modulating the NLRP3-regulated transforming growth factor- signaling pathway on interstitial cystitis/bladder pain syndrome Hung-Jen Shih, Chao-Yuan Chang, Chung-Howe Lai, Chun-Jen Huang Biomedicine & Pharmacotherapy.2021