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Rapid weight loss can sometimes lead to the loss of lean muscle mass, which can negatively impact your metabolic rate
Bray, G.A., et al
These shortages mean that some people may need to change to a different medication or management plan
"PIONEER 1: Randomized Clinical Trial of the Efficacy and Safety of Oral Semaglutide Monotherapy in Comparison With Placebo in Patients With Type 2 Diabetes." Diabetes Care
It is very rare, but it could happen
What we can foresee is an annual cycling in and out of the GLP-1 drug universe not dissimilar to the cycling in/out of diets more generally
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