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When those junctions are compromised, by NSAIDs, alcohol, chronic stress, or repeated antibiotic courses, the result is a low-grade inflammatory state that shows up as bloating, systemic fatigue, food sensitivities, and immune dysregulation

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The kynurenine pathway.10.1017/S0007114514001858 74 CurtoMLionettoLNegroACapiMFazioFGiamberardinoMAet alAltered kynurenine pathway metabolites in serum of chronic migraine patients