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Divergent roles of SHP-2 in ERK activation by leptin receptors

This study is not intended to break the bubble of hope but to add a layer of precaution in their over-prescription. The study serves as a critical reminder that while these medications can provide significant health benefits, their potential risks warrant careful scrutiny and further research

Recently, it has been demonstrated that mice with a deletion of the GLP-1 receptor only in -cells, are resistant to the beneficial anti-diabetic effect of a vertical sleeve-gastrectomy ( It appears that only in RYGB and SG patients intestinal derived GLP-1 has a true endocrine role, while in healthy individuals, localized, paracrine and neuronal signals primarily define the GLP-1 physiology

For people with very active travel schedules or limited access to reliable refrigeration, oral medications offer more flexibility

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