This gene is located on chromosome 2q37.3 and is responsible for encoding D-2-hydroxyglutarate dehydrogenase, whose primary function is to convert D-2-hydroxyglutarate (D-2-HG) into -ketoglutarate [53]
Managing Side Effects: The most common side effectssuch as mild nausea, transient fatigue, or digestive changesare temporary
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For example, cardiology guidelines already emphasize overall cardiovascular risk rather than relying solely on individual markers like cholesterol levels
Randomized controlled trials have demonstrated 60 to 100% reductions in NTD cases when women consumed folic acid supplements in addition to a varied diet during the month before and the month after conception
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