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They work by attaching to receptors on cells and triggering targeted biological responses
PRKACB, Protein Kinase cAMP-Activated Catalytic Subunit Beta
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When glutathione levels are depleted, detox pathways may become less efficient, allowing oxidative stress and inflammatory signaling to persist across multiple organ systems
Furthermore, of the 201 variants with nucleotide substitutions, 200 were missense variants instead of nonsense variants, meaning that the mutations cause a change in amino acid rather than a premature termination of translation
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