In participants with obesity or overweight, withdrawing tirzepatide led to substantial regain of lost weight, whereas continued treatment maintained and augmented initial weight reduction [75]
Yamada C, Yamada Y, Tsukiyama K, Yamada K, Udagawa N, Takahashi N, et al
It depends on your business goals
It is in the hands of prescribing clinicians and patients to develop a comprehensive, whole-patient plan
And, with the dismal results of the clinical trials, do we have any reason to believe that a GLP-1-targeted strategy might do better
The 2014 NICHD multicenter RCT of 750 women established letrozole as first-line medical ovulation induction for PCOS, with cumulative live-birth rates of 27.5% versus 19.1% for clomiphene (Legro et al