Analytical guidance such as ICH Q2(R2) and ICH Q14 supports the broader principle that methods should be fit for purpose and properly documented [13] [14]
This, in turn, doubles the capacity of the available growth factors to promote signaling cascades necessary for mitogenesis (cell division), motogenesis (promotion of cellular motility), morphogenesis (structural development), neurogenesis (growth and development of nervous tissue), production of stem cells, and protection of a wide range of cells against injury
Available at: Last updated 1/12/2015
Those findings have made it one of the most talked-about compounds in regenerative medicine
Acute injuries may start improving by weeks 3 to 4 in many protocols
Therefore, the dosage charts of both medications may not be the same