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However, realgar exposure induced nephrotoxicity in mice by initiating ferroptosis, which was accompanied by iron accumulation, excessive ROS production, and inhibited expression of key ferroptosis regulators

Gori T, Dragoni S, Lisi M, Di Stolfo G, Sonnati S, Fineschi M, Parker JD

10.1182/blood-2002-08-2548 98 LiJ

Notably, aging-related AE1 protein conformational changes result in the appearance of a senescent-specific antigen recognized by autologous antibodies [75]

Usage: After cleansing, gently massage a pea-sized amount onto face and neck in upward strokes