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A subsequent study in 2000 evaluated AOD 9604 peptide in obese Zucker rats through daily exposure over 19 consecutive days

GH secretagogue was developed for therapy in osteoporosis and muscle wasting, but the official manufacturing of Ibutamoren was discontinued due to a lack of effectiveness in clinical studies

In the Phase 2b trial (2007, n=536) AOD-9604 showed weight reduction only 0.3 kg greater than placebo after 24 weeks