10.1136/gut.2007.147496 Gut 166 SheuS
Loperamide for severe episodes Loperamide (the active ingredient in Imodium) slows intestinal motility and reduces stool frequency
Exploring the association between dietary fruit intake and endometriosis: a systematic review and meta-analysis
Pairs sold Revenues (25,000 pairs $40 per pair) Total cost of shoes (25,000 pairs $29 per pair) Sales commissions on first 19,000 pairs (19,000 pairs $2 per pair) Sales commissions on additional 6,000 pairs [6,000 pairs ($2 + $1.50 per pair)] Total variable costs Contribution margin Fixed costs 3-44 $ 7.50 22,800 $912,000 25,000 $1,000,000 725,000 38,000 21,000 784,000 216,000 171,000 EA Operating income $ 45,000 Alternative approach: Breakeven point in units = 19,000 pairs Store manager and store supervisor receive commission of $1.50 ($1+$0.50) on 6,000 (25,000 19,000) pairs
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BPC-157 is studied for local tissue effects: angiogenesis at the injury site, growth-factor signaling, and tendon-bone interface healing in animal models