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Campione et al 20 found that enzyme glutathione-s-transferase-pi (GST-pi), present in keratinocytes and melanocytes, protects cells against tumor progressionnotably, sun exposure-associated melanoma cells

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GLP-1 (glucagon-like peptide-1) agonists are injectables that mimic the hormone glucagon, which the body produces to control blood glucose levels

These renal protective mechanisms establish GLP-1 receptor agonists as preferred treatments for diabetes care in individuals with varying degrees of kidney damage, with evidence endorsing their use down to an eGFR of 15 mL/min/1.73m2 for specific medications

doi: 10.1016/j.metabol.2018.01.005 35 NiSYuanYQianZZhongZLvTKuangYet al