However, not everyone agrees
Signal Transduct Target Ther 8:132
While it usually gets better with time, consistent fatigue should be discussed with a healthcare provider
Meanwhile, DPP-4 cleaves the two active forms of GLP-1, GLP-1 (7-36 amide) and GLP-1 (737), into GLP-1 (9-36 amide) and GLP-1 (9-37), which have a relatively low affinity to GLP-1R and serve as the major circulating forms (3032)
You should reach out to your provider if you experience severe, unmanageable digestive upset, persistent vomiting, signs of dehydration, severe abdominal pain, or symptoms of low blood sugar
GLP-1 injections like semaglutide and tirzepatide