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Some stop because of side effects, coverage, cost, or life circumstances

While an individualized approach is necessary, further studies are required to understand how to effectively apply the combination approach and which cohort of people with obesity will benefit the most

doi:10.1111/ijd.12999 Allen J, Bradley RD

Consider obtaining serial CK levels

Quick comparison: Injection: Once weekly FDA-approved 2021 Most long-term data Max dose 2.4 mg Pill: Once daily FDA-approved December 2025 ~16.6% average weight loss in trials No needles required Both forms require a prescription

Introduction Starting a weight loss journey is an empowering step, but it often comes with a learning curve regarding how your body reacts to new medications