Treatment strategies primarily involve reducing the extent of lipid peroxidation, decreasing iron ion concentrations, disrupting iron transport, and regulating the expression of ferroptosis-related proteins
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Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinoma
In addition, differential mRNA expression of splice variants of the excitatory amino acid transporters EAAT1 and EAAT2 was observed in pyramidal neurons of the anterior cingulate cortex in the schizophrenia post-mortem brain [110]
Brain-derived neurotrophic factor in patients with Huntingtons disease