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Bachhawat AK, Thakur A, Kaur J, Zulkifli M

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DSIP is of key interest as it was developed to help combat oxidative stress and normalize myocardial contractility

For example, a study should not claim a calcium mechanism unless calcium was measured, and it should not claim a cAMP mechanism unless cAMP or a closely linked marker was measured

Impressively, it generated a bright fluorescent protein, esmGFP, sharing just 58% sequence identity with known proteins, representing an evolutionary gap of approximately 500 million years (Hayes et al., 2025)