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7 Mitochondrial metabolism does not predict poor outcomes following surgery alone

PubMed PMID: 14988435

As a key commensal bacterium for maintaining gut barrier integrity, the reduction of Akkermansia may exacerbate hyperandrogenemia and ovulatory dysfunction in PCOS by increasing LPS translocation, triggering ovarian macrophage pyroptosis and interferon- (IFN-)-mediated inflammatory responses, thereby disrupting steroid hormone synthesis, promoting granulosa cell apoptosis, and exacerbating hyperandrogenemia and ovulatory dysfunction in PCOS

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Lall et al

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