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Description

In its Complete Response Letter (CRL), the regulator highlighted specific CMC issues that must be satisfactorily resolved before the application can be approved

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The treatment is commonly available in subcutaneous injections, but alternative forms such as sublingual options have recently emerged

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PMCID: PMC1975347

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If you have Leber's hereditary optic neuropathy, you should avoid cyanocobalamin forms of B12

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This ratio maps a 250 mcg dose to 10 units on a U-100 syringe

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