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Its principal mechanisms include enhancing insulin secretion in response to meals, inhibiting glucagon release, and slowing gastric emptying

It should be noted that the protocol was not registered at the registry of systematic reviews/meta-analyses (PROSPERO)

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(in women), blood pressure greater than 130/85 mmHg, fasting triglyceride level (higher than 150 mg/dL), HDL level less than 50 mg/dL, and fasting blood sugar more than 100 mg/dL [22]

This participant subsequently withdrew but completed the scheduled follow-up visit, including all safety assessments

People taking certain meds, like iron chelators, should also avoid high dose vitamin C supplements