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Lifting weights or performing bodyweight exercises sends a direct signal to muscles that they are needed, overriding the catabolic signals created by calorie restriction
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Sex-related differences in how the body handles semaglutide also appear to be important
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They work by: Slowing gastric emptying , which prolongs feelings of fullness Reducing appetite through effects on brain centres that regulate hunger Improving insulin secretion and glucose metabolism Potentially reducing food intake and affecting eating behaviours These injections are administered subcutaneously, typically once weekly (semaglutide) or once daily (liraglutide), and have been approved by the MHRA for weight management in adults with a BMI 30 kg/m, or 27 kg/m with weight-related comorbidities, as an adjunct to reduced-calorie diet and increased physical activity
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