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One observational study conducted in the UK showed a 0.51% reduction in HbA1c and a 5.8-kg reduction in weight, with one in six patients discontinuing insulin after 26 weeks of exenatide-insulin combination therapy

Weight loss is important, but clinicians may also consider A1C, blood pressure, lipids, cardiovascular risk, liver fat, tolerability, medication interactions, quality of life, and long-term maintenance

Employer-sponsored health plans are not required to cover obesity treatment

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