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Insulated packaging with ice packs maintains reduced temperatures during transit
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](https://figures.semanticscholar.org/29d09f90ef3987dc57b0a42c826c18e1d3328e94/100-Figure5%E2%80%931-1.png)
Electrolyte drinks or oral rehydration solutions can also help if there is frequent vomiting or diarrhea
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](http://www.acc.org/-/media/6A3DE9DD4AF444CFBDE5C1B9B69FEC0F.jpg)
Sci Rep (2016) 6:37789
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](https://media.licdn.com/dms/image/v2/D4E22AQFHa_ISuoWV0g/feedshare-shrink_800/feedshare-shrink_800/0/1680853996204?e=2147483647&v=beta&t=iG0dwSM4wrE9OqXj__dWrF_ecAXkAPy0oyAiJHXhGg4)
Never use tap water
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](https://www.mdpi.com/pharmaceuticals/pharmaceuticals-18-00399/article_deploy/html/images/pharmaceuticals-18-00399-g001-550.jpg)
Shaking creates violent agitation that denatures proteins through a process called foaming degradation
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](https://pbs.twimg.com/media/Fr_v4X6WAAAKmGv.jpg)
doi:10.1038/s41564-021-00880-5 Zhang Y, Liu R, Chen Y, et al
![pioneer plus semaglutide SELECT Trial PDF] Effect of Additional Oral](https://www.researchgate.net/publication/362041112/figure/fig4/AS:11431281086813806@1664330878187/Key-efficacy-outcomes-of-the-global-PIONEER-studies-PIONEER-1-5-and-PIONEER-7-8-a.png)
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