13 The benefits derived from preserving muscle mass during GLP-1 therapy are not merely about counteracting a potential negative aspect of weight loss
Advisory committee meetings may be convened to get external expert opinions, particularly if the safety profile raises questions (as the dysesthesia signal might)
That's a real risk
However, it is early-stage evidence
Studies have shown reduction in heart disease, diabetes, dementia, fatty liver, sleep apnea, asthma, addiction, and more
Emerging research may also reveal new applications for GLP-1 beyond alcohol cravings, such as its impact on other substance use disorders, such as cocaine and opioid addictions