Nevertheless, GPXs-like were localised in various cellular compartments of Arabidopsis (cytosol, mitochondria, chloroplasts, peroxisomes, and apoplast) (Rodriguez Milla et al
Given the ancient origin of the Ca 2+ -based signaling, which evolutionary developed earlier than the mitochondrial apoptotic toolkit whose emergence cannot be dated back to the times earlier than eukaryogenesis and acquisition of an endosymbiotic mitochondrion, it can be assumed that the Ca 2+ toolkit takes over a key role in cell death signaling in terminally differentiated mitochondria-free erythrocytes
Arch Toxicol 2023;97:1397-412
10.3390/antiox10040595 26 HandyD
Am J Ther 12:5666 Farrell G, Cooksley W, Powell L (1979) Drug metabolism in liver disease: activity of hepatic microsomal metabolizing enzymes
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