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[19] DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors) such as sitagliptin, linagliptin, or saxagliptin represent oral alternatives that enhance incretin activity through a different mechanism
Fatigue that persists beyond the first 4-6 weeks, or fatigue that gets worse over time, usually means you are not eating enough
Beneficial microbes in the colon ferment the resistant starch
By activating both incretin pathways simultaneously, tirzepatide enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetitemechanisms that collectively improve glycaemic control and promote weight loss
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The most important question is not simply, Which treatment is newest? The better question is, Which treatment gives me the safest, most realistic, and most durable chance of success? Bottom line: GLP-1 pills may be a helpful option for many patients, especially those who want to avoid injections
