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Yes, they are generally very safe when given by trained professionals

This may be at room temperature [20-25C (68-77F)] or refrigerated [2-8 C (36 -46 F)]

208 An open crossover trial in 22 subjects with fibromyalgia found 200 mg of CoQ10 (as ubiquinone) twice daily (in a supplement that also contained vitamins B2, B6, B9, B12, and E) for three months reduced pain, fatigue, and sleep disturbance compared with no treatment

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I was also low ferritin, border line for zinc and my folate was good

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