Fluid retention should be considered, particularly in patients with heart failure, chronic kidney disease, or those experiencing peripheral oedema
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But researchers have suggested several possible reasons, including genetics and taking other medications that promote weight gain
Zepbound also targets GIP, a hormone that helps to regulate blood sugar levels and metabolism
The neural pathways involved in GLP-1 receptor-mediated reduction in food intake include feeding centers in the hypothalamus and hindbrain, the mesolimbic reward system (such as the ventral hippocampus), and certain forebrain regions, including the medial prefrontal cortex [14, 15]
The prescription requirement underscores the importance of a thorough medical evaluation before starting any medication