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The decreased levels of LAC in subjects with MDD are linked to shorter leukocyte telomere length (LTL), increased body mass index (BMI), and higher reported rates of childhood trauma and are predictive of lack of antidepressant responses as assessed using the Hamilton depression rating scale-21

This is the sweet spot for the majority of people on GLP-1 therapy

Tirzepatide may lead to greater average weight loss, but "those differences are real yet secondary if you can't afford the drug or stop it because of side effects," says Srivastava

We do not have data that supports that it comes before because we haven't sampled that much in the beginning

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