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The human body produces GHK naturally

351 Most SERDs with acrylic side chains are discontinued after phase 1 clinical trials due to limited efficacy and uncontrollable side effects, presenting significant challenges in developing new oral SERDs

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There has been evidence that intraperitoneal injection of Ex-4 protected against ischemia-induced neuronal apoptosis potentially by upregulating expression of the GLP-1R mainly in GABAergic interneurons or astrocytes in the hippocampal CA1 region of gerbils (77)

Ten Kulve JS, Veltman DJ, van Bloemendaal L, Groot PFC, Ruh HG, Barkhof F, et al