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In physiology, detoxification is the body's continuous, built-in machinery for processing and excreting toxins the liver's two-phase conjugation system, the kidneys' filtration, bile flow into the gut, sweat, and antioxidant defenses such as glutathione

The aim of this study is to investigate the protective effects of bromelain on oxidative stress and inflammation in an experimental model of lower limb ischemia-reperfusion injury

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These findings provide limited support for prior work suggesting sex-related variation in stimulant response and tolerability (Rapoport and Groenman, 2025