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Knowing what they are prevents them entirely

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It is important to note that, in the other large type 2 diabetes cardiovascular outcome trials, there were no statistically significant associations with the use of GLP-1/GIP agonists and negative eye outcomes

But the cost issue pales compared to the safety concern

The legal and regulatory landscape remains fluid, and policies may change

We often have some data on a single peptide (or at least a plausible mechanism), but very little high-quality human evidence that stack A + stack B produces additive benefitor does so safely