Studies show that GLP-1 therapy works by addressing insulin resistance and obesity-related inflammationconditions absent in metabolically healthy, normal-weight people
Clinical Evidence: Blood Pressure Reductions in GLP-1 Trials The LEADER trial, which followed over 9,000 people taking liraglutide (a similar GLP-1 drug), documented average systolic blood pressure drops of 23 mmHg within the first weeks of treatment
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4 Key secondary endpoints included 4 : Noninferiority of tirzepatide 5 mg once weekly to semaglutide 1 mg once weekly for glycemic control at 40 weeks
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