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Glutathione S-transferase alpha 4 induction by activator protein 1 in colorectal cancer
Interestingly, previous transcriptional analysis uncovered that AITC treatment affected the expression profile of certain genes involved in the regulation of cell cycle 23 , indicating the phytochemical-induced growth inhibition might be an indirect consequence of cell cycle misregulation due to GSH depletion
Research also shows that Epithalon can affect mitochondrial function and energy metabolism in cell models
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Side effects are rare and usually mild, such as slight soreness at the injection site
Mechanistically, its effects cluster around vascular remodeling, nitric-oxide (NO) signaling, extracellular-matrix repair, and inflammation control
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