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The importance of 3-AR was verified when long-term treatment with AOD9604 in 3-AR knockout mice failed to produce the changes in body weight and increase in lipolysis observed in wild-type control mice
In adipose tissue, inhibition of NNMT suppresses de novo lipogenesis, normalizes fat content, and improves insulin sensitivity 2-3
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Dispose of the container according to local regulations when it is three-quarters full
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A smaller injected amount is not proven equal to a larger oral amount
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