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Yeah, so if we go back over time over the last decade its gone from around 30,000 to just shy of a million people in the US and that equates to somewhere around 7% of adults currently taking or having claimed to have taken GLP-1 medication specifically for weight loss
That figure is contested: a 2026 Cell Reports Medicine analysis found no disproportionate muscle loss, with relative muscle improving
Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus
Discontinuation may lead to weight regain and reversal of health benefits
