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R Substrates glucuronidated by UGTs include: Acetaminophen (Tylenol) Bilirubin (heme degradation product) Estrogens (estradiol, estrone, estriol) Morphine and opioids NSAIDs (ibuprofen, naproxen) Thyroid hormones (T3, T4) There are four UGT families: UGT1A, UGT2A, UGT2B, and UGT3A

Despite some reports on the similarities between senescence and eryptosis at the morphological level [67], intracellular Ca 2+ elevation [74], Ca 2+ -driven activation of Gardos channels [70], PS exposure [76], or ROS contribution [71], senescence of erythrocytes cannot be considered an RCD of these cells and should be clearly distinguished from eryptosis

Jan 2019;32(1(Supplementary)):277-283

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